Thumbs is the story of Isaac Graber, a young man who in protest against having been stripped of any emotional, intellectual or spiritual context loses a grip on his sanity and mutilates himself. With the help of a psychologist suffering his own dilemma, Isaac struggles to regain some equilibrium by unraveling the knot of his past and thereby coming to terms with the reasons for his dissociation and the mutilation itself. These two men grappling with their personal demons and each other create sparks on the stage.