It's 1822. A fur trader named Alexis St Martin gets shot (on accident) and ends up with an open wound in his chest, opening directly to his stomach. His doctor, William Beaumont, uses him and his wound to conduct studies on digestion for the next 11 years. And yes, this really happened. Plus, there’s a framing device of a bunch of other fur traders telling each other this story and acting it out while they travel. It’s a ride.